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KMID : 0390119940340020315
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Journal of Pusan Medical College
1994 Volume.34 No. 2 p.315 ~ p.324
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Glucose Tolerance Test in Essential Hypertension
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Abstract
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Authors investigated the glucose tolerance test in 31 cases of essential hypertension and 30 cases of normal controls who had been admitted the ward of internal medicine. Pusan National Uniersity Hospital.
Plasma glucose levels in hypertensive patients and controls at fasting and 30, 60, 90 and 120 minutes after loading of glucose were 87.5mg/dl, 82.4mg/dl, 138.1 mg/dl 127.6mg/dl, 1467.2mg/dl 139.6mg/dl, 142.4mg/dl 130mg/dl, and 123.5mg/dl 118.8mg/dl respectively. Plasma glucose levels in hypertensive patients were higher in each time course than controls but were statistically not significant. Hypertensive patients of overweight group (BMI≥25) and normal weight group at fasting and 30, 60, 90 and 120 minutes after loading of glucose were 82.8mg/dl 82.4mg/dl. 161.3mg/dl 127.6mg/dl, 167.8mg/dl 139.6mg/dl, 145.2mg/dl, 130mg/dl, and 122.7mg/dl 118.8mg/dl, respectively.
Hypertensive patients of overweight group showed statistically higher concentration of plasma glucose levels compared with normal weight group in 30 and 60 minutes (p<0.05). Other parameters of the patients ie, age, level of blood pressure, duration of disease and each group of hypertensive retinopathy did not show significant relation to the glucose tolerance curve, but in comparison of paired group of I, II and III IV, paired group I, II showed significantly higher glucose concentration than controls and paired group III, IV in 120 minutes (p<0.05) and paired group III, IV showed significantly higher glucose concentration than controls in 30 minutes (p<0.05).
These results suggest the presence of some tendency of disturbed glucose turnover in patients with essential hypertension and further studies will be continued.
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KEYWORD
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